Current Projects
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Jurisica
2013-present -
Arthritis Society Canada: Contributions of distinct cell populations in the infrapatellar fat pad to knee osteoarthritis: Relationship with disease stage, sex and obesityM Kapoor, R Gandhi, I Jurisica
2024-2027 -
ERA-NET Neuron: Disease-predisposing or resilience-promoting? Decoding the systems biology and behavioural predictors and determinants of the tipping point of stressMB Muller, H Sork, I Hovatta, N Gassen, J Bohacek, I Jurisica
2024-2027 -
ORF: The Fibrosis Repair TeamMcCulloch, Hinz, Bozec, Jurisica, Kapus
2023-2028 -
CIHR Project Grant: Contribution of synovial fibroblast cell subsets to the pathogenesis of knee osteoarthritisKapoor, Gandhi, Jurisica
2023-2027 -
The Cure Parkinson’s Trust: Repurposing rifabutin as a disease-modifying therapy for Parkinson’s diseaseL. Kalia, I. Jurisica, J. Brotchie, S. Kalia
2022-2024 -
CIHR: Diabetes Mechanisms and Translational Solutions to investigate the Central role of muscle autophagy in metabolism and musculoskeletal healthWoo, Kapoor, Cheung, Jurisica, Wong, Usmani, Rockel
2021-2026 -
CIHR Project Grant: Identification and characterization of microRNAs essential for the development and fitness of chemoresistant AMLSalmena, Jurisica, Gabra
2021-2026
Past Projects
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CIHR Team Grant: Cannabis-based precision medicine for osteoarthritis therapyClarke, Kapoor, Bhatia, Bonin, Davis, Fish, Furlan, Jurisica, Kotra, Zywiel, Leroux
2020-2024 -
Horizon2020-RISE: Integrative structural biology of pathological tau protein, an appealing therapeutic target for Alzheimer´s disease modifying drugsZeman, Hritz
2020-2024 -
Genome Canada DIG: Interactome mapping of disease-related proteins using split intein-meidated proteinn ligation (SIMPL)Stagljar, Jurisica, Kislinger
2020-2024 -
Improving Outcomes by Understanding Flares in Psoriatic Arthritis: Patient-centric Approach with In-home Monitoring of Symptoms, Biomarkers and Physical ActivityChandran, Jurisica, Passalent, Perruccio, Kulasingam, Cameron
2021-2023 -
CIHR/Eranet: Multi-level integrative ‘omics to identify biomarkers in a Schizophrenia and other major psychosesPoschmann, Schulze, Jurisica
2020-2023 -
National Health and Medical Research Council of Australia: Artificial intelligence-enhanced prediction of early indicators of metastasis in lung cancer using platelet genomicsVafaee, Hudson, Jurisica
2020-2023 -
NSERC: Novel methods for integrative computational biologyJurisica
2018-2023 -
CIHR Project Grant: Identifying Metabolomic Markers of Disease Activity in Psoriatic Disease using Solid Phase Microextraction - Liquid Chromatography - High Resolution Mass SpectrometryChandran, Kulasingam, Jurisica, Eder, Rosen, Cook, Boyle, Pawliszyn
2021-2022 -
CIHR Catalyst Grant: Understanding who does and does not respond to an interprofessional education and self-management model of care for chronic low back painPI: Raja Rampersaud, Anthony Perruccio, Co-A: I. Jurisica, C. Veillette
2020-2021 -
CIHR Priority Funding-The Canadian Epigenetics, Environment and Health Research Consortium (CEEHRC): Role and therapeutic potential of MicroRNA-34a-5p in knee osteoarthritisPI: M. Kapoor, Co-A: R. Gandhi, I. Jurisica
2020-2021 -
Genome Canada: Interactome mapping of disease-related proteins using split intein-mediated protein ligation (SIMPL)PI: I. Stagljar, I. Jurisica, T. Kislinger
2018-2021 -
Ontario Research Fund: The Next Generation Signalling Biology PlatformPI: I. Jurisica
2018-2021 -
Ontario Research Fund: Protein network analysis of cancer surfaceome - from interactions to drugsPI: I. Stagljar and I. Jurisica
2016-2020 -
National Psoriasis Foundation: Multi-omic Diagnostic Test for Psoriatic Arthritis in Psoriasis PatientsPI: V. Chandran; Co-Is: D. Gladman, P. Rahman, L. Eder, Rosen, Jurisica, Kulasingam, R. Cook, Bansback, Boyle;
2019-2020 -
National Psoriasis Foundation: Imaging Sub-phenotypes of Psoriatic Arthritis and their Correlations with Molecular Signature – A Step Towards Precision MedicinePI: L. Eder; Co-Is: V. Chandran, R. Cook, I. Jurisica, P. Rahgman, I. Eshed;
2018-2019 -
CCSRI: A novel model of human brain metastasis from lung cancer: Discovering genes that regulate brain metastasisPI: Sheila Singh
2016-2019 -
Medicine by Design: Pathways to enhance the clinical utility of hematopoietic stem cell transplantationPI: J. Dick
2016-2019 -
Genome Canada: The Mammalian Membrane Two-Hybrid (MaMTH) Assay - an Advanced Proteomics Technology for Biomedical ResearchPI: I. Stagljar and I. Jurisica
2016-2019 -
Krembil Foundation: The Osteoarthritis Data Integration Platform (OADIP): Identifying and mapping genomic markers of osteoarthritisPI: I. Jurisica and C. Veillette
2016-2018 -
NSERC: Developing novel heuristic methods for integrative computational biologyPI: I. Jurisica
2013-2018 -
DOD: Optimizing Early-Phase Translational Ovarian Cancer Clinical Trials with Integrative Computational BiologyPI: A. Oza and I. Jurisica
2012-2017 -
CRC-CFI: Integrative cancer informaticsPI: I. Jurisica
2011-2018 -
McLaughlin Centre: Development of hybrid modeling approaches for identifying multicomponent targeted therapiesPI: I. Jurisica
2014/15 -
ORF-GL2: Cancer Gene Encyclopedia (CGEP): Computationally optimized characterization of cancer genes, proteins, their structure, function and interactions.PI: I. Jurisica, G. Bader, Co-applicants: L. Stein, Q. Morris
2010-2015 -
NIH: Growth Factor Receptor Signaling in Breast CancerPI: MC Hung
2010-2015 -
ORF-RE: Integrated Molecular Pathology of Targeted Cancer Therapy in Lung Cancer (IMP4-Lung Cancer)PI: M. Tsao, I. Jurisica, Co-applicants: F. Shepherd, G. Liu, T. Kislinger, M. Moran
April 2009-2015 -
McLaughlin Centre: Cancer prevention and treatment by molecular epidemiologyPI: I. Jurisica
2013-2014 -
CIHR: Diagnostic and prognostic biomarkers for epithelial ovarian cancerPI: I. Jurisica, A. Oza, Co-applicants: T. Kislinger, T. Colgan, A. Jurisicova
2009-2014 -
NIH: Development of an expert crystallization knowledge systemPI: E Snell
2009-2014 -
Jurisica, DeTitta, Luft, Snell, Glasgow, Fortier
2007-2014 -
CIHR: The interactome of the human G-protein coupled receptorsPI: I. Stagljar, Co-applicants: Bouvier, Michel, Jurisica, Igor
2011-2013 -
NSERC: Techna 2012: Information and Communication Technologies for HealthPI: I. Jurisica
2012 -
NSERC: Scalable intelligent systems for integrative analyses in computational biologyPI: I. Jurisica
2012-2013 -
CFI LOF: Integrative computational biology for cancer genomicsPI: I. Jurisica
2011 -
IBM International Foundation: Help Conquer CancerPI: I. Jurisica
2011 -
NSERC Discovery Grants: Integrative Computational BiologyPI: I. Jurisica
April 1, 2007-March 31 2012 -
CIHR Catalyst grant: Tools for efficient and effective network-based prediction of diagnostic and prognostic cancer signaturesPI: I. Jurisica, Co-applicants. Drs. M.S.Tsao and I. Stagljar
November 1, 2009-October 31, 2010 -
CIHR: Maternal lethal effect and human infertilityPI: A. Jurisicova, Co-applicants: I. Jurisica, E. Greenblat
July 2007-July 2010 -
Canada Foundation for Innovation/Ontario Research Fund: Comprehensive Systems Biology Approach to Profiling and Modeling of Cancer. A collaborative infrastructure for integrated translational research.PI: I. Jurisica, Principal users: Attisano, L., Bremner, R., Brown, T., Jurisica, I., Kislinger, T., Penn, L., Rottapel, R., Shaw, P., Tsao, M., Wrana, J.
2007 -
Canada Foundation for Innovation CRC/CFI/ORF Infrastructure - Integrative Computational BiologyPI: I. Jurisica
November 1, 2006 - October 31, 2011 -
NIH - the Center for High Throughput Structural Biology (U54 GM074899-01)PI: G. DeTitta, Co-PIs: Mark Dumont, Mark Sullivan, Eric Phizicky, Ethan Merritt, Sol Gruner, Igor Jurisica, Mike Soltis, Mike Malkowski, Joe &nb sp; Luft, Eddie Snell, Keith Hodgson.
July 1, 2005-2010 -
Genome Canada - The Dynactome: Mapping Spatio-Temporal Dynamic Systems in HumansPI: T. Pawson, J. Wrana, S. Li, I. Jurisica, J. Dennis
January, 2006 - 2009 -
OICR: Identification and characterization of genetic alterations at the stromal-epithelial interface in prostate cancer.PI: N. Fleshner; coPIs, T. Brown, S. Done, I. Jurisica, J. Sweet
May 2007-2010 -
NSERC Strategic Grant: Intelligent monitoring, diagnosis, and rehabilitation of stroke patients.PI: J. Glasgow, I. Jurisica, S. Scott
October 2006-2009 -
CIHR - Defining the canonical and non-canonical WNT signaling pathwaysPI: Attisano; I. Jurisica
July, 2005-2008 -
CIHR - Endoglin, ALK-1 and BMPRII networks: Role in vascular disordersPI: M. Letarte; I. Jurisica; J. Wrana
July, 2005-2010 -
CIHR - Myometrial programming: A new concept underlying the control of myometrial contractility during pregnancyPI: S. Lye; I. Jurisica; B. Langille
July, 2005-2010 -
CIHR - Functional characterization of androgen-altered genes with a putative role during early events in ovarian carcinogenesis.PI: T. Brown, Co-PIs: I. Jurisica, P. Shaw, M. Letarte
June 2005 - June 2009 -
CIHR - The next generation of gene transfer therapy for human nasopharyngeal cancer.PI: Fei-Fei Liu, Co-PIs: I. Jurisica, R. M. Reilly
2004-2008 -
National Cancer Institute of Canada - Novel Molecular Prognostic Markers and Potential Therapeutic Targets in Non-Small Cell Lung Cancer (# 015184)PI: M-S Tsao; Co-PIs: I. Jurisica, W. Lam, M. Johndston, S. Der (UT), M. Pintilie, D. Wigle, F. Shepherd; Additional authors: C.-Q. Zhu, B.P. Coe, J. Liu
2003-2008 -
DOD US Army - Integrated computational biology approach to marker selection for early detection and treatment of epithelial ovarian cancer. # OC040038PI: I. Jurisica, Co-applicants: T. Brown, A. Oza, P. Shaw, J. Wrana
November 15, 2004- November 15, 2007. -
NSERC Research Grant - Decision Support for Biomedical DomainsI. Jurisica
April 2002- March 2007 -
Ontario Cancer Research Network - Genomic and proteomic biomarkers of response to treatment with small molecule epidermal growth factor receptor inhibitors in non-small cell lung cancer; OCRN 03-APR-0324PI: M-S Tsao, Co-PIs: I. Jurisica, F. Blackhall, W. Newman, F. Shepherd, L. K. Seymour, M. Pintilie
September 2003- September 2006 -
NIH - Northeast Structural Genomics Consortium 2- Structural Genomics of Eukaryotic Model OrganismsPI: Gaetano Montelione, Co-PIs: Arrowsmith, Cheryl, Anderson, DeTitta, George, Edwards, Aled, Gerstein, Mark, Hendrickson, Wayne, Honig, Barry, Hunt, John, Jurisica, Igor, Kennedy, Michael A, Regan, Lynne, Rost, Burkhard, Szyperski, Thomas, Tong, Liang
July 1, 2005- July 1, 2006 -
GlaxoSmithKline – An integrated computational approach to identify important yeast proteinsPI: I. Jurisica
November 1, 2004-2005 -
IBM SUR grant – Life Sciences Discovery CentrePI: I. Jurisica
May 2005 -
IRIS - Intelligent Computational Methods for the Analysis of Gene Expression ProfilesPI: I. Jurisica, Co-PIs: J. Glasgow, R. Ng, H. Hoos
1/2002-2005 -
NIH - Northeast Structural Genomics Consortium - Structural Genomics of Eukaryotic Model OrganismsPI: Gaetano Montelione, Co-PIs: Arrowsmith, Cheryl, Anderson, DeTitta, George, Edwards, Aled, Gerstein, Mark, Hendrickson, Wayne, Honig, Barry, Hunt, John, Jurisica, Igor, Kennedy, Michael A, Regan, Lynne, Rost, Burkhard, Szyperski, Thomas, Tong, Liang
October 1, 2000 - August 31, 2005 -
IBM SUR Grant - Integrated computational biologyPI: I. Jurisica
5/2003 -
NSERC Strategic Grant - Knowledge Management and Decision Support for Crystal GrowthJ. Glasgow, I. Jurisica, S. Fortier, Industry collaborators: Evan Steeg of Molecular Mining Corporation; IBM Canada, Centre for Advanced Studies
1999-2003 -
IBM UPP Grant - Data mining, visualization and interpretation of high-throughput biological dataPI: I. Jurisica
9/2002 -
IBM UPP Grant - Knowledge Management in Biological DomainsPI: I. Jurisica
9/2001 -
IBM UPP Grant - Protein Crystallization Knowledge ManagementPI: I. Jurisica
9/2000 -
IBM SUR Grant - Decision-Support System for Crystallization Experiment DesignPI: I. Jurisica
12/1999 -
NSERC Research Grant - Decision Support for Biomedical DomainsPI: I. Jurisica
3/1998-3/2002 -
NSERC Equipment Grant - Molecular Scene Analysis and Macromolecular CrystallizationJ. Glasgow, S. Fortier - Queen's U, I. Jurisica - U of Toronto
April 2000 -
CITO Research Grant - Knowledge Discovery for Crystal GrowthJ. Glasgow, S. Fortier - Queen's U, I. Jurisica - U of Toronto
April 1 2000 - March 31 2002 -
NSERC Equipment Grant - Computational Techniques for BioinformaticsJ. Glasgow, S. Fortier - Queen's U, I. Jurisica - U of Toronto
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CITO Research Grant - CBR: Knowledge Management and ApplicationsJ. Glasgow, S. Fortier - Queen's U, N. Cercone - U Waterloo, S. Matwin, R. Holte - Uof Ottawa, I. Jurisica - U of Toronto
April 1 1998 - March 31 2000
All contents copyright Jurisica Lab, Krembil Research Institute, UHN. Last modified December 2023
